Carbon nanodots interference with lactate dehydrogenase assay in human monocyte THP-1 cells

Carbon nanodots interference with lactate dehydrogenase assay in human monocyte THP-1 cells

BACKGROUND Carbon nanodots (CD), a new class of carbon nanomaterials with sizes below 10 nm, have recently attracted wide attention due to their superiority in water solubility, chemical inertness, and resistance to photobleaching. As a result, CD has found important and wide applications in energy, catalysis, biological labeling, bioimaging and drug delivery. On the other hand, due to the lack...

effect of eicosapentaenoic acid on the expression of abcg1 gene in the human monocyte thp-1 cells.

cardiovascular disease (cvd) is the leading cause of death and disability in developed countries. atherosclerosis is the major cause of cvd, accounting for about half of the attributed deaths. cholesterol homeostasis is one of the most important factors in atherosclerosis. atp-binding cassette transporters cholesterol. omega (ω) 3 fatty acids are important ligands for regulation of abc transpor...

9-cis retinoic acid induces monocyte chemoattractant protein-1 secretion in human monocytic THP-1 cells.

Monocyte migration and activation are regulated by monocyte chemoattractant protein-1 (MCP-1). Prior studies have shown MCP-1 expression is modulated by a variety of ligands that act through extracellular receptors. In the current study, we show 9-cis retinoic acid (RA), a ligand for the nuclear hormone receptor retinoid X receptor (RXR) and retinoic acid receptor (RAR), markedly induces the ex...

Monocyte/Macrophage (THP-1) Cells Expressed and Activated in Human Isoforms of Jun Kinase Are Differentially

Lactate dehydrogenase isoenzymes in normal and malignant human lymphoid cells.

Intracellular lactate dehydrogenase (LD) isoenzyme patterns were studied in the malignant cells of patients with a variety of lymphoid malignancies. These were compared with intracellular LD isoenzyme patterns of normal lymphoid cells and were also correlated with immunologic cell surface marker characteristics. Results showed that, in general, the malignant B cells of Burkitt's lymphoma and th...